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Polymorphism of tumour necrosis factor-alpha (TNF-α) at position –308 in relation to ankylosing spondylitis

✍ Scribed by G. M. G. M. VERJANS; B. M. N. BRINKMAN; C. E. M. VAN DOORNIK; A. KIJLSTRA; C. L. VERWEIJ


Book ID
108698568
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
246 KB
Volume
97
Category
Article
ISSN
0009-9104

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Polymorphism at position −308 of the tum
✍ Benedicte Mugnier; Nathalie Balandraud; Albert Darque; Chantal Roudier; Jean Rou 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 62 KB 👁 1 views

## Abstract ## Objective To test whether the G‐to‐A polymorphism at position −308 in the promoter of the tumor necrosis factor α (TNFα) gene influences response to infliximab therapy in patients with rheumatoid arthritis (RA). ## Methods We genotyped 59 RA patients by polymerase chain reaction a