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Associations of tumour necrosis factor alpha promoter polymorphisms at position −308 and −238 with clinical characteristics of chronic hepatitis C

✍ Scribed by C-Y. Dai; W-L. Chuang; L-P. Lee; S-C. Chen; N-J. Hou; Z-Y. Lin; M-Y. Hsieh; M-Y. Hsieh; L-Y. Wang; W-Y. Chang; M-L. Yu

Book ID
108885924
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
52 KB
Volume
13
Category
Article
ISSN
1352-0504

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Tumor necrosis factor alpha promoter pol
Tumor necrosis factor alpha promoter polymorphism at position -238 is associated with chronic active hepatitis C infection
✍ Höhler, Thomas; Kruger, Anke; Gerken, Guido; Schneider, Peter M.; zum Büschenfel 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 45 KB 👁 1 views

Tumor necrosis factor alpha (TNF-alpha) is involved in the pathogenesis of chronic hepatitis C virus infection. The gene for TNF-alpha is encoded in the major histocompatibility locus (MHC). Two polymorphisms at positions -308 and -238 in the TNF-alpha promoter region might influence TNF-alpha expre