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POLYMORPHISM OF THE 5' FLANKING REGION OF THE HLA-DQA1 GENE IN COELIAC DISEASE

✍ Scribed by Paz Bettinotti, M. ;Kolek, A. ;Brünnler, G. ;Haas, P. ;Paul, C. ;Hochberger, M. ;Bartova, A. ;Kimura, A. ;Sasazuki, T. ;Albert, E. D.


Book ID
114831110
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
460 KB
Volume
20
Category
Article
ISSN
0960-7420

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DNA polymorphisms in the 5′-flanking reg
✍ Giovanna Pozzo; Carmela Perfetto; Maria Neve Ombra; Guang-Zhi Ding; John Guardio 📂 Article 📅 1992 🏛 Springer-Verlag 🌐 English ⚖ 903 KB

The HLA-DQA1 gene exhibits haplotype-specific restriction fragment polymorphisms due to DNA rearrangements. We found that some of these polymorphisms extend into the 5' flanking region of the gene and are distinct from other HLA-DQA1 related DNA polymorphisms so far reported. Sequencing of genomic D