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Polymorphism in the promoter region of DQA1 gene: A study in celiac disease patients

✍ Scribed by Petronzelli, F.; Kimura, A.; Tassone, C.; Sasazuki, T.; Ferrante, P.; Arma, D.; Mazzilli, M.C.


Book ID
123394574
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
113 KB
Volume
36
Category
Article
ISSN
0198-8859

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DNA polymorphisms in the 5β€²-flanking reg
✍ Giovanna Pozzo; Carmela Perfetto; Maria Neve Ombra; Guang-Zhi Ding; John Guardio πŸ“‚ Article πŸ“… 1992 πŸ› Springer-Verlag 🌐 English βš– 903 KB

The HLA-DQA1 gene exhibits haplotype-specific restriction fragment polymorphisms due to DNA rearrangements. We found that some of these polymorphisms extend into the 5' flanking region of the gene and are distinct from other HLA-DQA1 related DNA polymorphisms so far reported. Sequencing of genomic D