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Polymorphism in the 5′-flanking region of HLA-DQA1 in german patients with systemic lupus erythematosus

✍ Scribed by Yao, Z.; Kimura, A.; Haas, J.P.; Hochberger, M.; Hartung, K.; Volgger, A.; Keller, E.; Bettinotti, M.dlP.; Albert, E.

Book ID
121979188
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
127 KB
Volume
36
Category
Article
ISSN
0198-8859

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The HLA-DQA1 gene exhibits haplotype-specific restriction fragment polymorphisms due to DNA rearrangements. We found that some of these polymorphisms extend into the 5' flanking region of the gene and are distinct from other HLA-DQA1 related DNA polymorphisms so far reported. Sequencing of genomic D