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Polymorphism of CYP1A1 gene and susceptibility to childhood acute lymphoblastic leukemia in Egypt

✍ Scribed by Agha, Adel; Shabaan, Howyda; Abdel-Gawad, Eman; El-Ghannam, Doaa

Book ID
120549369
Publisher
Informa plc
Year
2013
Tongue
English
Weight
234 KB
Volume
55
Category
Article
ISSN
1042-8194

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## Abstract Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. The genetic factors underlying the susceptibility to this disease remain elusive. The enzymes CYP2E1, MPO and NQO1 are involved in the biotransformation of a variety of xenobiotics present in organic solvents, tobac