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Polymorphisms of DNA repair genes and susceptibility to acute childhood lymphoblastic leukemia

✍ Scribed by Carlos Alberto Scrideli; Luiz Gonzaga Tone

Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
88 KB
Volume
33
Category
Article
ISSN
0145-2126

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## Abstract Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. The genetic factors underlying the susceptibility to this disease remain elusive. The enzymes CYP2E1, MPO and NQO1 are involved in the biotransformation of a variety of xenobiotics present in organic solvents, tobac