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Genetic polymorphisms ofNQO1,CYP1A1andTPMTand susceptibility to acute lymphoblastic leukemia in a Tunisian population

✍ Scribed by Slah Ouerhani, Nouha Cherif, Ikbel Bahri, Ines Safra…


Book ID
120751366
Publisher
Springer
Year
2012
Tongue
English
Weight
232 KB
Volume
40
Category
Article
ISSN
0301-4851

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## Abstract Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. The genetic factors underlying the susceptibility to this disease remain elusive. The enzymes CYP2E1, MPO and NQO1 are involved in the biotransformation of a variety of xenobiotics present in organic solvents, tobac