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Polymorphism at the position -308 of TNF-α gene influences outcome of infliximab therapy in rheumatoid arthritis

✍ Scribed by B Mugnier, D Reviron, A Darque, N Balandraud, C Roudier, J Roudier

Book ID: 120707072
Publisher: BioMed Central
Year: 2004
Tongue: English
Weight: 527 KB
Volume: 6
Category: Article
ISSN: 1478-6354
DOI: 10.1186/ar1114

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## Abstract ## Objective To test whether the G‐to‐A polymorphism at position −308 in the promoter of the tumor necrosis factor α (TNFα) gene influences response to infliximab therapy in patients with rheumatoid arthritis (RA). ## Methods We genotyped 59 RA patients by polymerase chain reaction a

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