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Gene polymorphism at position −308 of the tumor-necrosis -factor-α (TNF-α) in Multiple Sclerosis and it's influence on the regulation of TNF-α production

✍ Scribed by N. Braun; U. Michell; B.P. Ernst; R. Metzner; A. Bitsch; F. Weber; P. Rieckmann


Book ID
116125917
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
386 KB
Volume
215
Category
Article
ISSN
0304-3940

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Polymorphism at position −308 of the tum
✍ Benedicte Mugnier; Nathalie Balandraud; Albert Darque; Chantal Roudier; Jean Rou 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 62 KB 👁 1 views

## Abstract ## Objective To test whether the G‐to‐A polymorphism at position −308 in the promoter of the tumor necrosis factor α (TNFα) gene influences response to infliximab therapy in patients with rheumatoid arthritis (RA). ## Methods We genotyped 59 RA patients by polymerase chain reaction a