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Polymorphic variations in exon 10 of the luteinizing hormone receptor: Functional consequences and associations with breast cancer

✍ Scribed by Djura Piersma; Miriam Verhoef-Post; Maxime P. Look; André G. Uitterlinden; Huibert A.P. Pols; Els M.J.J. Berns; Axel P.N. Themmen

Book ID
116734210
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
272 KB
Volume
276
Category
Article
ISSN
0303-7207

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## Abstract Menopausal hormone therapy (HT) is associated with increased breast cancer risk among postmenopausal women. Nuclear receptors are involved in steroid hormone‐ and xenobiotic‐mediated signal transduction playing a crucial role in regulating gene expression. Therefore, variations within t