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Functional polymorphisms in the TERT promoter are associated with risk of serious ovarian and breast cancer

✍ Scribed by (author); (author);Beesley, Jonathan (author);Pickett, Hilda (author);Johnatty, Sharon (author);Chen, Xiaoqing (author);Li, Jun (author);Rider, David (author);Stutz, Michael (author);Lambrecht, Diether (author);Chang-Claude, Jenny (author);Dork, Thilo (author);Goodman, Marc (author);Kiemmney, Bart (author);Bandera, Elisa (author);Kelemen, Linda (author);Wang-Gorke, Shan (author);Campbell, Ian (author);Gayther, Simon (author);Ramus, Susan (author);Goode, Ellen (author);Reddel, Roger (author);Chenevix-Trench, Georgia (author)

Book ID: 115027847
Publisher: Springer Nature
Year: 2012
Tongue: English
Weight: 83 KB
Volume: 10
Category: Article
ISSN: 1897-4287
DOI: 10.1186/1897-4287-10-s2-a86

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## Communicated by Stephen Chanock Matrix metalloproteinases (MMPs) play important roles in cancer initiation and development. Several polymorphisms in the promoters of a number of MMP genes, which can affect the respective MMP production in an allele-specific manner, have been well characterized.