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Polymorphic variation in the androgen receptor gene: Association with risk of testicular germ cell cancer and metastatic disease

✍ Scribed by Åke Västermark; Yvonne Lundberg Giwercman; Oskar Hagströmer; Ewa Rajpert De-Meyts; Jakob Eberhard; Olof Ståhl; Gabriella Cohn Cedermark; Hamideh Rastkhani; Gedske Daugaard; Stefan Arver; Aleksander Giwercman

Book ID: 116430530
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 162 KB
Volume: 47
Category: Article
ISSN: 0959-8049
DOI: 10.1016/j.ejca.2010.08.017

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## Abstract Changes in the length of a polymorphic trinucleotide (CAG) repeat in the androgen receptor (AR) gene, which may lead to altered transactivation of the AR gene, have been implicated to play a role in the pathogenesis of several forms of endocrine cancer and certain reproductive disorders

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