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Polymorphisms in CAG active allele length of the androgen receptor gene are not associated with increased risk of endometrial cancer

✍ Scribed by Woong Ju; Seung Cheol Kim


Book ID
113513058
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
60 KB
Volume
172
Category
Article
ISSN
0165-4608

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The human androgen receptor (AR) gene possesses 2 trinucleotide repeats of CAG and GGN in exon 1. The CAG repeat corresponds to a polyglutamine tract in the N-terminal region of the receptor, that affects its transcriptional efficiency. The GGN repeat codifies for a polyglycine tract, and affects th