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Polymorphic CAG repeat length in the androgen receptor gene and association with neurodegeneration in a heterozygous female carrier of Kennedy’s disease

✍ Scribed by KarenJ. Greenland; Jonathan Beilin; Julian Castro; PaulN. Varghese; JeffreyD. Zajac

Publisher: Springer
Year: 2004
Tongue: English
Weight: 269 KB
Volume: 251
Category: Article
ISSN: 0340-5354
DOI: 10.1007/s00415-004-0266-x

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## Abstract Changes in the length of a polymorphic trinucleotide (CAG) repeat in the androgen receptor (AR) gene, which may lead to altered transactivation of the AR gene, have been implicated to play a role in the pathogenesis of several forms of endocrine cancer and certain reproductive disorders

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