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Polymer-supported triacetoxyborohydride: a novel reagent of choice for reductive amination

✍ Scribed by Sukanta Bhattacharyya; Sunil Rana; Owen W Gooding; Jeff Labadie


Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
180 KB
Volume
44
Category
Article
ISSN
0040-4039

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✦ Synopsis


A novel polymer-supported triacetoxyborohydride reagent for reductive amination of aldehydes and ketones is reported. The bound reagent was found to be shelf-stable and provided broad scope and reactivity in reductive amination reactions under mild reaction conditions. Streamlined protocols for its application in reductive amination reactions using both primary and secondary amines are described.


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