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A novel polymer-supported sulfur-transfer reagent for the synthesis of phosphorothioates

✍ Scribed by Zhaoda Zhang; Yongxin Han; Jimmy X Tang; Jin-yan Tang


Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
76 KB
Volume
43
Category
Article
ISSN
0040-4039

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✦ Synopsis


A commercially available and inexpensive compound, 3-amino-1,2,4-dithiazole-5-thione (ADTT), has been attached onto a hydroxyl resin via a succinic acid linker. The polymer-supported ADTT is an efficient sulfur-transfer reagent for the solution-phase synthesis of phosphorothioates.


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