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Polymer-Supported Synthesis of Cyclic Ethers: Electrophilic Cyclization of Tetrahydrofuroisoxazolines

✍ Scribed by Beebe, Xenia; Chiappari, Cynthia L.; Olmstead, Marilyn M.; Kurth, Mark J.; Schore, Neil E.

Book ID
125896474
Publisher
American Chemical Society
Year
1995
Tongue
English
Weight
1008 KB
Volume
60
Category
Article
ISSN
0022-3263

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Optimum conditions for the preparation of aryl-alkyl ethers from N-protected aminoalcohols using polymer-supported triphenylphosphine have been developed. In contrast to previous literature reports, it was discovered that the progress of this reaction is greatly improved when a tertiary amine base i