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Synthesis of Cyclic Ethers Utilizing a Cyclization–Fragmentation Strategy

✍ Scribed by Denise A. Ockey; David R. Lane; Juliette A. Seeley; Neil E. Schore

Book ID
108379555
Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
206 KB
Volume
56
Category
Article
ISSN
0040-4020

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## Abstract This paper describes a simple biomimetic strategy to prepare small cyclic proteins containing multiple disulfide bonds. Our strategy involves intramolecular acyl transfer reactions to assist both the synthesis and fragmentation of these highly constrained cyclic structures in aqueous so