Polymer-supported Mitsunobu ether formation and its use in combinatorial chemistry
✍ Scribed by Viktor Krchňák; Zuzka Flegelová; Aleksandra S. Weichsel; Michal Lebl
- Book ID
- 103403958
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 214 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
The synthesis of aryl ethers from phenols and alcohols using polymer-bound triphenylphosphine and diethyl azodicarboxylate (DEAD) is described. The polymer-bound triphenylphosphines are easily removed by filtration from the reaction products. This method is operationally simple and provides the prod
## Abstract Two metathesis catalysts, RuCl~2~(PCy~3~)(NHC)(CHPh) (1) [NHC=1‐(2,4,5‐trimethylphenyl)‐3‐(6‐hydroxyhexyl)‐imidazol‐2‐ylidene] and Mo(N‐2,6‐__i‐__Pr~2~‐C~6~H~3~)(CHCMe~2~Ph)(BIPHEN) (2) [BIPHEN=(__R__)‐3,3′‐di‐__t‐__butyl‐5,5′,6,6′‐tetramethyl‐2,2′‐biphenolate) have been immobilized on
Polymer supported 1, 5, .0]dec-5-ene (PTBD) was used as a base and a reagent scavenger for rapid synthesis of aryl ethers from phenols and alkyl or aryl halides. This method provides a simple reaction operation, and generally high purity of reaction product in good yield.