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Polyanions inhibit binding of human autoantibodies to certain cellular proteins

✍ Scribed by A.E. Kabakov; Y.B. Griaznova; V.A. Saenko; A.M. Poverenny

Book ID
107908257
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
348 KB
Volume
26
Category
Article
ISSN
0165-2478

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The influence of charged polymers on the reaction of immunoglobulins from human lupus sera with cellular proteins was investigated in this study. Through immunoblotting it was shown that polyanions (dextran sulfate, heparin, polyinosinic acid) and polylysine inhibited autoantibody binding to several