[Molecular Biology Intelligence Unit] Po
β Caiafa, Paola
π Library
π
2006
π Springer US
β¦ LIBER β¦
π
Poly(ADP-Ribosyl)ation
β Scribed by Alexander BΓΌrkle M.D. (auth.)
- Publisher
- Springer US
- Year
- 2006
- Tongue
- English
- Leaves
- 259
- Series
- Molecular Biology Intelligence Unit
- Edition
- 1
- Category
- Library
β¬ Acquire This Volume
No coin nor oath required. For personal study only.
β¦ Synopsis
Poly(ADP-Ribosyl)ation comprises 19 chapters written by leading international experts in the field and is richly illustrated. Extensive bibliography is given in each chapter.
β¦ Table of Contents
Enzymes in Poly(ADP-Ribose) Metabolism....Pages 1-12
PARP-2: Structure-Function Relationship....Pages 13-31
Targeting the Poly (ADP-Ribose) Glycohydrolase (PARG) Gene in Mammals....Pages 32-40
DNA Damage Signaling through Poly(ADP-Ribose)....Pages 41-50
Roles of Poly(ADP-Ribose) Metabolism in the Regulation of Centrosome Duplication and in the Maintenance of Neuronal Integrity....Pages 51-60
Functional Interactions of PARP-1 with p53....Pages 61-66
Dynamic Interaction between PARP-1, PCNA and p21 waf1/cip1 ....Pages 67-74
PARP-1 as Novel Coactivator of NF-ΞΊB in Inflammatory Disorders....Pages 75-90
PARP and Epigenetic Regulation....Pages 91-102
PARP and the Release of Apoptosis-Inducing Factor from Mitochondria....Pages 103-117
Genome Degradation by DNAS1L3 Endonuclease....Pages 118-131
NAD: Metabolism and Regulatory Functions....Pages 132-140
PARP-1 and the Shape of Cell Death....Pages 141-152
Poly(ADP-Ribose) Polymerase (PARP) and Excitotoxicity....Pages 153-163
Poly(ADP-Ribose) Polymerase and Ischemia-Reperfusion Injury....Pages 164-183
Role of Poly(ADP-Ribose) Polymerase Activation in the Pathogenesis of Inflammation and Circulatory Shock....Pages 184-202
Role of Poly-ADP-Ribosylation in Cancer Development....Pages 203-217
PARP Inhibitors and Cancer Therapy....Pages 218-233
Poly(ADP-Ribosyl)ation and Aging....Pages 234-241
β¦ Subjects
Medical Microbiology; Human Genetics; Biochemistry, general; Cell Biology
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