Point Mutation of c-Ki-ras Oncogene in Gastric Adenoma and Adenocarcinoma with Tubular Differentiation
β Scribed by Kihana, Toshimasa ;Tsuda, Hitoshi ;Hirota, Teruyuki ;Shimosato, Yukio ;Sakamoto, Hiromi ;Terada, Masaaki ;Hirohashi, Setsuo
- Book ID
- 108579288
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1991
- Tongue
- English
- Weight
- 508 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0910-5050
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## Abstract Pointβmutational activation of the cβKiβ__ras__ protoβoncogene has been shown to be rare in human hepatocellular carcinoma, the most common primary liver cancer and one usually associated with chronic viral infection. To reveal the association of cβKiβ__ras__ activation with cholangioca
## Abstract We have used the polymerase chain reaction and dideoxynucleotide sequencing to amplify and sequence exons 1 and 2 of the cβKiβ__ras__ protoβoncogene from the normal Syrian golden hamster. Similar methods were employed to screen for the presence of point mutations in the cβKiβ__ras__ onc