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Point mutation and homozygous deletion of PTEN/MMAC1 in primary bladder cancers

✍ Scribed by Cairns, Paul; Evron, Ella; Okami, Kenji; Halachmi, Naomi; Esteller, Manel; Herman, James G; Bose, Shikha; Wang, Steven I; Parsons, Ramon; Sidransky, David


Book ID
110061361
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
316 KB
Volume
16
Category
Article
ISSN
0950-9232

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The PTEN/MMAC1 gene, located on human chromosome 10q23, has recently been implicated as a candidate tumor suppressor gene in human cancers. In the present study, 12 uterine cancer cell lines and 87 uterine cancers of various grades and histological type were analyzed for PTEN/MMAC1 gene. Three of 44