PTEN/MMAC1/TEP1 mutations in human primary renal-cell carcinomas and renal carcinoma cell lines
β Scribed by Kei-ichi Kondo; Masahiro Yao; Kazuki Kobayashi; Shinsuke Ota; Minoru Yoshida; Shigeki Kaneko; Masaya Baba; Naoki Sakai; Takeshi Kishida; Satoshi Kawakami; Hiroji Uemura; Yoji Nagashima; Yukio Nakatani; Masahiko Hosaka
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- French
- Weight
- 188 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Cyclin-D1 over-expression represents one of several common alterations in the G 1 -S transition associated with malignancies. Conclusive evidences indicate that cyclin D1 is a proto-oncogene and the gene is amplified or rearranged in different tumour types. Since very little is known about aberratio
Reduced expression of the major-histocompatibility-complex(MHC)-class-I antigens has been demonstrated in renalcell carcinoma (RCC), and appeared to be associated with deficiencies in the expression and function of different components of the MHC-class-I-antigen-processing pathway and poor recogniti
## BACKGROUND. The cyclin D1 gene is amplified and/or overexpressed in several types of human cancer, including cancers of the breast, esophagus, head, and neck. However, the role of cyclin D1 in prostate cancer has not been previously studied in detail. METHODS. Six human prostate cancer cell lin
The MN/CA9 (G250) gene expressed in the normal alimentary tract in a tissue-specific manner is often activated in renal cell carcinomas. To cast light on the activation mechanism, we examined the methylation status of this gene in seven human renal cell carcinoma cell lines and three normal kidney t