This paper presents a program written in the BASIC language for the Radio Shack TRS-80 PC-l or the Sharp PC 1211 pocket computers for fitting the Hill equation to experimental data. The program is based on a procedure involving a combination of an optimization technique and nonlinear regression. The
Pocket computer program for fitting the Michaelis-Menten equation
β Scribed by Enrique G. Oestreicher; Gerson F. Pinto
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 464 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0010-4825
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β¦ Synopsis
This paper presents a program written for the Radio Shack TRS80 or the Sharp PC 1211 pocket computers for fitting the MichaelieMenten equation to experimental data by a non-linear regression analysis. The program determines the kinetic parameters Km and Vm, their standard errors and the residual standard error. In addition it performs a simulation of a kinetic experiment using the parameter values previously determined. Fitting of rate equations Enzyme kinetics Non-linear regression analysis Pocket computer
π SIMILAR VOLUMES
A computer program for the estimation of kinetic parameters in enzymatic rate laws is described. The program includes statistical tests for the reliability of the optimal parameter values and for bias error due to a poor model. A set of criteria for selecting between models is given. The program is
## Abstract The MichaelisβMenten rate equation can be found in most general biochemistry textbooks, where the time derivative of the substrate is a hyperbolic function of two kinetic parameters (the limiting rate __V__, and the Michaelis constant __K__~M~) and the amount of substrate. However, fund