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Pocket computer program for fitting the Hill equation

✍ Scribed by Gerson F. Pinto; Enrique G. Oestreicher

Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
414 KB
Volume
14
Category
Article
ISSN
0010-4825

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✦ Synopsis

This paper presents a program written in the BASIC language for the Radio Shack TRS-80 PC-l or the Sharp PC 1211 pocket computers for fitting the Hill equation to experimental data. The program is based on a procedure involving a combination of an optimization technique and nonlinear regression. The program determines precisely all three parameters of the Hill equation and in addition, it performs a simulation of the kinetic experiment using the parameter values previously estimated, calculating the sum of squares of residuals. Fitting of rate equations Allosteric enzymes Pocket computer Enzyme kinetics

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