๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

A convenient computer program for fitting enzymatic rate laws to steady-state data

โœ Scribed by Michael C. Kohn; lawrence E. Menten; David Garfinkel

Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
578 KB
Volume
12
Category
Article
ISSN
0010-4809

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โœฆ Synopsis

A computer program for the estimation of kinetic parameters in enzymatic rate laws is described. The program includes statistical tests for the reliability of the optimal parameter values and for bias error due to a poor model. A set of criteria for selecting between models is given. The program is easy to learn, convenient to use and modify, inexpensive to use, and widely applicable. The behavior of the program with the correct and an incorrect model was examined using simulated test data. The effects of experimental design and experimental error were investigated.

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