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P(MeNCH2CH2)3N: An efficient nonionic superbase for Wittig and Wittig-Horner reactions

✍ Scribed by Zhigang Wang; John G. Verkade

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
133 KB
Volume
9
Category
Article
ISSN
1042-7163

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✦ Synopsis

The strong non-ionic base P(MeNCH 2 -CH 2 ) 3 N 1 is an efficient base for conversion of [RCH 2 PPh 3 ]X and RCH 2 P(O)(OEt) 2 to their corresponding ylides under mild conditions. Reaction of the ylides (generated in situ) with benzaldehyde give the corresponding alkenes in high yield.

πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: P(MeNCH2CH2)3N: An
ChemInform Abstract: P(MeNCH2CH2)3N: An Efficient Nonionic Superbase for Wittig and Wittigβ€”Horner Reactions.
✍ Zhigang Wang; John G. Verkade πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 33 KB πŸ‘ 2 views

P(MeNCH 2 CH 2 ) 3 N: An Efficient Nonionic Superbase for Wittig and Wittig-Horner Reactions. -The strong non-ionic title base effectively deprotonates triphenylphosphonium salts (I) and phosphonates (IV) under mild conditions. Reaction of the ylides generated with aldehydes provides an efficient a