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Platelet-Derived Growth Factor Enhances Granulopoiesis Via Bone Marrow Stromal Cells

✍ Scribed by Mo Yang; Karen Li; Audrey Carmen Lam; Patrick Man Pan Yuen; Tai Fai Fok; Colin N. Chesterman; Beng H. Chong

Book ID
105675246
Publisher
Carden Jennings Publishing
Year
2001
Tongue
English
Weight
157 KB
Volume
73
Category
Article
ISSN
0925-5710

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✍ Sherry L. Abboud πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 815 KB

MBA-2, bone marrow-derived endothelial stromal cells, express platelet-derived growth factor (PDGF) A and B chain mRNAs and secrete PDCF activity that is induced by TGF-beta. Either chain of the PDGF molecule could modulate hematopoiesis and stromal cell growth. lntracellular pathways that regulate