Platelet-derived growth factor enhances demineralized bone matrix-induced cartilage and bone formation
β Scribed by R. Howes; J. M. Bowness; G. R. Grotendorst; G. R. Martin; A. H. Reddi
- Book ID
- 110554549
- Publisher
- Springer
- Year
- 1988
- Tongue
- English
- Weight
- 661 KB
- Volume
- 42
- Category
- Article
- ISSN
- 1432-0827
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π SIMILAR VOLUMES
Platelet-derived growth factor (PDGF) is a polypeptide found in a variety of tissues, including bone, where it could act as an autologous regulator of skeletal remodeling. Therefore, a recombinant B chain homodimer of human PDGF was studied for its effects on bone formation in cultured rat calvariae
## Abstract Plateletβrich plasma (PRP) represents an autologous source of growth factors essential for bone regeneration. The clinical efficacy of PRP is, however, unpredictable, and this is likely due to the inefficient and inconsistent delivery of PRPβderived growth factors. Previous investigatio