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Platelet-Derived Growth Factor Requirement for Cultured Descendants of Rabbit Stromal Bone Marrow Precursors

โœ Scribed by Yu. F. Gorskaya; V. G. Nesterenko; O. V. Lebedinskaya


Book ID
106356788
Publisher
Springer US
Year
2005
Tongue
English
Weight
265 KB
Volume
139
Category
Article
ISSN
0007-4888

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MBA-2, bone marrow-derived endothelial stromal cells, express platelet-derived growth factor (PDGF) A and B chain mRNAs and secrete PDCF activity that is induced by TGF-beta. Either chain of the PDGF molecule could modulate hematopoiesis and stromal cell growth. lntracellular pathways that regulate