Platelet-derived growth factor (PDGF) is a potent activator for cells of mesenchymal origin. PDGF stimulates chemotaxis, proliferation, and new gene expression in monocytes-macrophages and fibroblasts in vitro, cell types considered essential for tissue repair. Therefore, we analyzed the influence o
Platelet-derived growth factor — A growth factor with an expanding role in health and disease
✍ Scribed by Habenicht, A. J. R. ;Salbach, P. ;Janßen-Timmen, U. ;Blattner, C. ;Schettler, G.
- Book ID
- 105265187
- Publisher
- Springer-Verlag
- Year
- 1990
- Tongue
- English
- Weight
- 767 KB
- Volume
- 68
- Category
- Article
- ISSN
- 1432-1440
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## Abstract Platelet‐derived growth factors (PDGFs) are paracrine growth factors mediating epithelial–mesenchymal interactions and exerting multiple biological activities which include cell proliferation, motility, and differentiation. As previously demonstrated, PDGFs act during embryonic developm