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Platelet Aggregation Inhibiting and Anticoagulant Effects of Oligoamines, XXIV: Interactions between Oligosydnone Imines and Albumine or Phospholipids

✍ Scribed by Klaus Rehse; Daniela Piechocki


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
318 KB
Volume
327
Category
Article
ISSN
0365-6233

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✦ Synopsis


Oligosydnone imines are strongly bound to albumine (a < 1%) in pure water. In saline, however, this effect is abolished (a -80%). 4,4'-Propy-**) Pan of the PhD thesis D. Piechocki, Fu Berlin, 1992


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✍ Klaus Rehse; Antje Martens πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 English βš– 338 KB

## Abstract The synthesis of ten tris‐sydnone imine derivatives, unknown up to now, is described. All compounds are alkyl or arylalkyl substituted in 3‐position of the sydnone imine. The most powerful agent was the 3‐propyl derivative 6c. It inhibits the aggregation of human platelets induced by co