Platelet [3H]imipramine binding in autism and schizophrenia
β Scribed by A. Weizman; N. Gonen; S. Tyano; G. A. Szekely; M. Rehavi
- Book ID
- 104889157
- Publisher
- Springer
- Year
- 1987
- Tongue
- English
- Weight
- 370 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0033-3158
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Platelet ['Hlimipramine binding, a putative biological marker for depression, varies considerably among healthy control subjects. This study examined whether changes associated with the menstrual cycle could account for part of this variability. No significant relationship was found between B,,, or
The presence of high affinity binding sites for 3H-imipramine (3H-IMI) in human platelets is by now well established. This recognition site is associated with the transporter for 5HT, and may be a biological marker in depression. Fluctuations of other putative biological markers of depression (i.e.