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Planar cell polarity genes,Celsr1-3, in neural development

✍ Scribed by Jia Feng, Qi Han, Libing Zhou


Book ID
113100724
Publisher
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
Year
2012
Tongue
English
Weight
397 KB
Volume
28
Category
Article
ISSN
1673-7067

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## Abstract Closure of the neural tube is essential for normal development of the brain and spinal cord. Failure of closure results in neural tube defects (NTDs), common and clinically severe congenital malformations whose molecular mechanisms remain poorly understood. On the other hand, it is incr