Plakinidines: Cytotoxic alkaloid pigments from the fijian sponge plakortis sp.
โ Scribed by Robert R. West; Charles L. Mayne; Chris M. Ireland; Linda S. Brinen; Jon Clardy
- Book ID
- 104222274
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- French
- Weight
- 261 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
It&a, New Yor ' 14868-1901 A&rack A complete rtructwe aasiqnment of the Plabidinea A-C b dercribed. Becently, a plethora of t&-a-and penta-cyck tbed rin2 aIkaloId pigmente have been iaoIated from a wide variety of marine orgmiam11.6 The large majority of these
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Plakotenin. a new carboxylic acid with cytotoxic acrivity was isolated from the Okinawan marine sponge PIak$s sp. and the struc~vc elucidated on the basis of spectroscopic data. Marine sponges of the genus Plakortis have been a rich source of a variety of unique bioactive compounds such as polycycli
2D-NMR spectroscopic data is reported for the haliclonacyclamines A -D (1)-( ) and for two bismethiodide adducts ($) and ( ). The structures of two new alkaloids, halicionacyclamines C (3) and D (4), which are the 15,16-dihydro analogues of the haliclonacyclamines A (1) and B (2) are described. Revi