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PL3-3 Silencing of Irf7 expression in breast cancer cells promotes bone metastases

✍ Scribed by P.J. Hertzog; B.N. Bidwell; N. Withana; N. Mangan; D. Andrews; S. Samarajiwa; R. Anderson; B.S. Parker

Book ID
116399769
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
133 KB
Volume
52
Category
Article
ISSN
1043-4666

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## Abstract Survivin is recognized as an attractive target in cancer therapy because of its selective overexpression in the majority of tumors. Upregulated expression of this protein correlates with increased tumor grade, recurrence risk and decreased cancer patients survival. In this study, we ass