Transforming growth factor-β1-dependent
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Kiyoshi Wakahara; Hiroshi Kobayashi; Tatsuo Yagyu; Hidenori Matsuzaki; Toshiharu
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Article
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2004
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John Wiley and Sons
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English
⚖ 617 KB
## Abstract The net balance between urokinase‐type plasminogen activator (uPA) and plasminogen activator inhibitor type‐1 (PAI‐1) has been implicated in tumor cell invasion and metastasis. To elucidate the mechanism of the transforming growth factor‐β1 (TGF‐β1)‐dependent up‐regulation of PAI‐1 expr