Cleavage and inactivation of antiapoptot
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Susumu Rokudai; Naoya Fujita; Yuichi Hashimoto; Takashi Tsuruo
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Article
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2000
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John Wiley and Sons
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English
โ 173 KB
The oncogene Akt/PKB/RAC-PK is a serine/threonine kinase that mediates survival signals and has protective effects against apoptosis induced by a variety of stimuli. The kinase activity of Akt has been demonstrated to be critical in transmitting survival signals. We found that Akt protein was down-r