Effects of CAY10404 on the PKB/Akt and MAPK pathway and apoptosis in non-small cell lung cancer cells
β Scribed by Yongseon CHO; Mee-Ja PARK; Mira PARK; Sun Seek MIN; Jaeyong YEE; Chan KIM; Min-Soo HAN; Seung-Ho HAN
- Book ID
- 108965124
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 437 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1323-7799
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Nonβsmall cell lung cancer cells (NSCLC) are more resistant to anticancer treatment as compared with other types of cancer cells. Recently (HemstrΓΆm __et al__., Exp Cell Res 2005;305:200β13) we showed that apoptosis of U1810 NSCLC cells induced by the staurosporine analog PKC 412 correl
The pathway consisting of retinoblastoma protein (pRB), cyclin D1 and p16 (RB pathway) which is involved in the phosphorylation of pRB plays an important role in G 1 /S progression. The disruption of this RB pathway has been reported in several types of human neoplasm. An immunohistochemical study o