Age-related differences in insulin-like
β
Muyao Li; Jen-Fu Chiu; Jessica Gagne; Naomi K. Fukagawa
π
Article
π
2008
π
John Wiley and Sons
π
English
β 575 KB
## Abstract Advanced age is a major risk factor for atherosclerosis, but how aging per se influences pathogenesis is not clear. Insulinβlike growth factorβ1 receptor (IGFβ1R) promotes aortic vascular smooth muscle cell (VSMC) growth, migration, and extracellular matrix formation, but how IGFβ1R sig