Pitavastatin: Efficacy and Safety Profiles of A Novel Synthetic HMG-CoA Reductase Inhibitor
โ Scribed by Kajinami, Kouji ;Takekoshi, Noboru ;Saito, Yasushi
- Book ID
- 109106096
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 134 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0897-5957
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๐ SIMILAR VOLUMES
## Abstract A new synthetic method for the preparation of pitavastatin is described. The approach circumvents various synthetic problems associated with the buildup of the 3,5โdihydroxyโC~7~ acid side chain of HMGโCoA reductase inhibitors (statins). The use of the C~6~โamide derivative **5** instea
On p. 1074, in Scheme 3, the correct formula of NK-104 should be as follows: 2) On p. 1077, line 16 should read as follows: (390 ml) was cooled to ร 788, and 1.6m BuLi in hexane (374.4 g, 881 mmol) was added under 3) On p. 1078, line 15 should read as follows: As HPLC revealed the presence of mor