ANGIOGENIC EFFECTS OF A NEW HMG-COA REDUCTASE INHIBITOR, PITAVASTATIN
β Scribed by Takayuki Shindo; Yuelan Zhang; Hiroshi Iwata; Pei Niu; Satoshi Iimuro; Norifumi Takeda; Ryozo Nagai
- Book ID
- 116341957
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 57 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1054-8807
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## Abstract A new synthetic method for the preparation of pitavastatin is described. The approach circumvents various synthetic problems associated with the buildup of the 3,5βdihydroxyβC~7~ acid side chain of HMGβCoA reductase inhibitors (statins). The use of the C~6~βamide derivative **5** instea
On p. 1074, in Scheme 3, the correct formula of NK-104 should be as follows: 2) On p. 1077, line 16 should read as follows: (390 ml) was cooled to Γ 788, and 1.6m BuLi in hexane (374.4 g, 881 mmol) was added under 3) On p. 1078, line 15 should read as follows: As HPLC revealed the presence of mor