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Pinacol Coupling Reaction of β-Halo-α,β-unsaturated Aldehydes Promoted by TiI4.

✍ Scribed by Makoto Shimizu; Hiroshi Goto; Ryuuichirou Hayakawa


Publisher
John Wiley and Sons
Year
2003
Weight
235 KB
Volume
34
Category
Article
ISSN
0931-7597

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Cross-pinacol-type coupling reactions be
✍ Kazuhiko Takai; Ryotaro Morita; Hiroshi Matsushita; Chika Toratsu 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 120 KB 👁 1 views

Treatment of an alpha,beta-unsaturated ketone and an aldehyde with chromium(II) chloride and R(3)SiCl in DMF gives cross-pinacol-type coupling products, 1,2-diols selectively. The anti/syn ratios of the produced 1,2-diols are shown to depend on the reaction temperature: at lower temperatures, the an