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Stereoselective Cross Pinacol-Type Coupling between α,β-Unsaturated Ketones and Aldehydes Mediated by Chromium(II) and R3SiCl

✍ Scribed by Kazuhiko Takai; Ryotaro Morita; Chika Toratsu


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
106 KB
Volume
113
Category
Article
ISSN
0044-8249

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Cross-pinacol-type coupling reactions be
✍ Kazuhiko Takai; Ryotaro Morita; Hiroshi Matsushita; Chika Toratsu 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 120 KB

Treatment of an alpha,beta-unsaturated ketone and an aldehyde with chromium(II) chloride and R(3)SiCl in DMF gives cross-pinacol-type coupling products, 1,2-diols selectively. The anti/syn ratios of the produced 1,2-diols are shown to depend on the reaction temperature: at lower temperatures, the an