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Pilot Scale Synthesis of a Novel Nonpeptide Angiotensin II Receptor Antagonist

โœ Scribed by Zanka, Atsuhiko; Nishiwaki, Masanori; Morinaga, Yasuhiro; Inoue, Takayuki

Book ID
118026575
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
177 KB
Volume
2
Category
Article
ISSN
1083-6160

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๐Ÿ“œ SIMILAR VOLUMES

Facile synthesis of novel nonpeptide ang
Facile synthesis of novel nonpeptide angiotensin II receptor antagonists
โœ Ling-Chun Yang; Guan-Xin Zhang; Nan-Zhi Zou; Chuan-Min Qi ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Journal of Heterocyclic Chemistry ๐ŸŒ English โš– 65 KB

## Abstract A series of Losartan analogues **1โ€12** with different functional groups were synthesized and characterized. In comparison with the previous reports, the synthetic procedures described in this paper have been optimized as follows below: 1) preparation of aromatic amine **15** and **18**