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Pharmacology of CS-866, a novel nonpeptide angiotensin II receptor antagonist

โœ Scribed by Makoto Mizuno; Toshio Sada; Masahiro Ikeda; Norio Fukuda; Masaaki Miyamoto; Hiroaki Yanagisawa; Hiroyuki Koike


Book ID
115890418
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
649 KB
Volume
285
Category
Article
ISSN
0014-2999

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Facile synthesis of novel nonpeptide ang
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## Abstract A series of Losartan analogues **1โ€12** with different functional groups were synthesized and characterized. In comparison with the previous reports, the synthetic procedures described in this paper have been optimized as follows below: 1) preparation of aromatic amine **15** and **18**