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PIK3CA is implicated as an oncogene in ovarian cancer

✍ Scribed by Shayesteh, Laleh; Lu, Yiling; Kuo, Wen-Lin; Baldocchi, Russell; Godfrey, Tony; Collins, Colin; Pinkel, Daniel; Powell, Bethan; Mills, Gordon B.; Gray, Joe W.

Book ID
109826559
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
236 KB
Volume
21
Category
Article
ISSN
1061-4036

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## Abstract The PI3K‐AKT pathway is activated in a variety of human cancers, resulting in disturbance of cell growth, proliferation and survival. Among the factors affecting the pathway, the __K‐Ras__ mutation and __PIK3CA__ mutation are the most common oncogenic alterations in colorectal cancer. W