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PIK3CA as an oncogene in cervical cancer

✍ Scribed by Ma, Yen-Ying; Wei, Sung-Jen; Lin, Yu-Chen; Lung, Jia-Chyi; Chang, Ting-Chang; Whang-Peng, Jacqueline; Liu, Jacqueline M; Yang, Deng-Mei; Yang, Wen K; Shen, Chen-Yang

Book ID
110063921
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
185 KB
Volume
19
Category
Article
ISSN
0950-9232

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## Abstract Mutation of __PIK3CA__, the gene coding for the p110Ξ± catalytic subunit of phosphoinositide 3‐kinase (PI3K), has been reported in a limited range of human tumors. We now report that __PIK3CA__ is also mutated in esophageal tumors. Single‐strand conformational polymorphism (SSCP) and den